Erratum to: the effects of the DDS-1 strain of lactobacillus on symptomatic relief for lactose intolerance - a randomized, double-blind, placebo-controlled, crossover clinical trial

Erratum This erratum is in response to comments made to our recently published study “The Effects of the DDS-1 Strain of Lactobacillus on Symptomatic Relief for Lactose Intolerance A Randomized, Double-Blind, PlaceboControlled, Crossover Clinical Trial” [1]. The Frese et. al. study [2] compares autochthonous strains of Lactobacillus to DDS-1, an allochthonous strain. This is a significant aspect of their study, as an allochthonous strain would generally not be expected to establish in higher levels compared with a strain naturally found in the human gastrointestinal tract. The comment “the DDS-1 strain of L. acidophilus to be superior to other strains of lactobacillus in the ability to establish in the human gastrointestinal (GI) tract [2]” refers to its ability to colonize the GI tract compared with other allochthonous strains, which in other studies have not been shown to establish well in the human gastrointestinal tract. While it is true what the reader states that “authors found that only in a small number of subjects did the strain survive gastric passage, and the strain did so in lower numbers and in fewer subjects than the other Lactobacillus species tested” this is expected as an allochthonous strain (eg DDS-1) would not be expected to demonstrate superior colonization compared with a strain naturally found in the human gastrointestinal tract (e.g. Lactobacillus reuteri and mucosae). With regard to the statement “However, it has been previously reported that the DDS-1 strain does successfully establish in the human gastrointestinal tract [2].” This statement is true. It is important to note that